Epithelial Protein Lost in Neoplasm, EPLIN, the Cellular and Molecular Prospects in Cancers

نویسندگان

چکیده

Epithelial Protein Lost In Neoplasm (EPLIN), also known as LIMA1 (LIM Domain And Actin Binding 1), was first discovered a protein differentially expressed in normal and cancerous cell lines. It is now to be key the progression metastasis of certain solid tumours. Despite slow pace understanding biological role cells body systems, well its clinical implications early years since discovery, recent have witnessed rapid progress mechanisms this cells, diseases indeed body. EPLIN has drawn more attention over past few with roles expanding from migration cytoskeletal dynamics, cycle, gene regulation, angiogenesis/lymphangiogenesis lipid metabolism. This concise review summarises discusses processes cancer.

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ژورنال

عنوان ژورنال: Biomolecules

سال: 2021

ISSN: ['2218-273X']

DOI: https://doi.org/10.3390/biom11071038